DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels

Advanced MaterialsVolume 27, Issue 23 p. 3513-3517 Communication DhITACT: DNA Hydrogel Formation by Isothermal Amplification of Complementary Target in Fluidic Channels Ho Yeon Lee, Ho Yeon Lee College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorHansaem Jeong, Hansaem Jeong College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorIl Young Jung, Il Young Jung College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorBora Jang, Bora Jang College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorYoung Chang Seo, Young Chang Seo Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701 Republic of KoreaSearch for more papers by this authorHaeshin Lee, Haeshin Lee Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701 Republic of KoreaSearch for more papers by this authorHyukjin Lee, Corresponding Author Hyukjin Lee College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaE-mail: hyukjin@ewha.ac.krSearch for more papers by this author Ho Yeon Lee, Ho Yeon Lee College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorHansaem Jeong, Hansaem Jeong College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorIl Young Jung, Il Young Jung College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorBora Jang, Bora Jang College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaSearch for more papers by this authorYoung Chang Seo, Young Chang Seo Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701 Republic of KoreaSearch for more papers by this authorHaeshin Lee, Haeshin Lee Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 305-701 Republic of KoreaSearch for more papers by this authorHyukjin Lee, Corresponding Author Hyukjin Lee College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750 Republic of KoreaE-mail: hyukjin@ewha.ac.krSearch for more papers by this author First published: 06 May 2015 https://doi.org/10.1002/adma.201500414Citations: 43Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract DNA hydrogel formation by isothermal amplification of complementary targets in microfluidic channels (DhITACT) is a new platform for rapid and accurate detection of infectious pathogens. DNA hydrogel is formed in situ within microfluidic channels by the isothermal rolling circle amplification process upon the selective binding of target strands from the biological fluid. Once the volume of DNA hydrogel sufficiently enlarges, it can selectively block the matching channels with target pathogens. Citing Literature Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description adma201500414-sup-0001-S1.pdf889.9 KB Supplementary Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume27, Issue23June 17, 2015Pages 3513-3517 RelatedInformation