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Erratum for “Combination of traditional mutation and metabolic engineering to enhance ansamitocin P‐3 production in Actinosynnema pretiosum” (Vol. 114, Issue 12, pp. 2794–2806)

细胞内 限制 化学 发酵 生物化学 工程类 机械工程
作者
Zhiqiang Du,Yuan Zhang,Zhi‐Gang Qian,Xiao Han,Jian‐Jiang Zhong
出处
期刊:Biotechnology and Bioengineering [Wiley]
卷期号:115 (10): 2668-2668
标识
DOI:10.1002/bit.26796
摘要

This erratum is being published to correct a typographical error in Figure 5d,e, which led to the wrong unit mg/g DCW being reported for malonyl-CoA and methylmalonyl-CoA concentrations. The correct unit for malonyl-CoA and methylmalonyl-CoA concentrations is μg/g DCW. The corrected version of Figure 5 for publication is provided below. Intracellular metabolite concentrations of UDP-glucose (a), AHBA (b), Glyceryl-S-ACP (c), Malonyl-CoA (d), and Methylmalonyl-CoA (e) in 250-ml shake flask fermentation of WT, M, and M-asm13–17:asmUdpg, *p < 0.05 On page 2800, “As shown in Figures 5d and 5e, the intracellular concentrations of malonyl-CoA and methylmalonyl-CoA in all the three strains were higher than other intermediates, implying that the supply of those two CoAs might be sufficient for AP-3 biosynthesis in the strains.” should read “As shown in Figure 5d,e, the intracellular concentration of malonyl-CoA at first and fourth day and that of methylmalonyl-CoA at first and second day in all the three strains had no significant difference, implying that the supply of those two CoAs might have no limiting effects on AP-3 biosynthesis in the strains.” All other parts are unchanged. The publisher regrets these errors. The published article can be found here: https://onlinelibrary.wiley.com/doi/full/10.1002/bit.26396.
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