An integrated nanoflower-like MoS2@CuCo2O4 heterostructure for boosting electrochemical glucose sensing in beverage

Excessive glucose in food poses a non-negligible threat to its inherent quality and human health, which makes it imperative to develop a highly sensitive sensor for real-time glucose detection. In this work, an integrated electrochemical glucose sensor based on a nanoflower-like MoS2@CuCo2O4 heterostructure was carefully constructed. Under optimal conditions, the as-fabricated sensor exhibited a high sensitivity of 1,303 μA mM−1 cm−2 over a wide range of 0.5–393.0 μmol/L, accompanied by a low determination limit (0.5 μmol/L) and short response time (2.1 s). The favorable sensing performance of the MoS2@CuCo2O4 nanocomposite-modified electrode in electrochemical analyses was attributed to the introduction of unique nanoflower-like heterostructure and the synergistic effects between MoS2 and CuCo2O4. Furthermore, the satisfactory applicability of this sensor in beverages was confirmed. These results demonstrate that the MoS2@CuCo2O4/GCE may be a promising platform for sensitive monitoring of glucose content in food samples.