亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Multiple infections with hepatitis A virus and development of rheumatoid arthritis among waste water treatment plant workers

类风湿性关节炎 医学 转氨酶 内科学 免疫学 生物 生物化学
作者
Dina Nadeem Abd‐Elshafy,Hala M. Raslan,Rola Nadeem,Mona Awad,S SHALABY,Mahmoud Mohamed Bahgat
出处
期刊:Journal of Infection in Developing Countries [Open Learning on Enteric Pathogens]
卷期号:16 (01): 187-195 被引量:1
标识
DOI:10.3855/jidc.15053
摘要

Introduction: In the present work, we studied the association between multiple exposure of waste water treatment plant workers to infection with existing hepatitis A virus in waste water and development of rheumatoid arthritis, taking in consideration number of working years as an indicator for frequency of exposure to infection, compared to non waste water treatment plant workers. Methodology: A total of 105 waste water treatment plant workers and 48 NWWTPWs were included in the study. Exclusion criteria were positivity for HBV and/or HCV IgG, negativity to HAV IgG and suffering from rheumatic diseases other than rheumatoid arthritis. Results: 96.2% of waste water treatment plant workers were anti-HAV-IgG positive, of whom 5 had high antibody titer indicating ongoing infection and were anti-HAV-IgM negative excluding primary infection. These 5 samples were further subjected to quantification of liver enzymes, glutamate oxaloacetate trasaminase and glutamate pyruvate transaminase and HAV-RT-PCR to check viremia and results showed increase of glutamate oxaloacetate trasaminase and glutamate pyruvate transaminase as well as viremea in all of them. Rheumatoid arthritis diagnosis was carried out by detection of C-reactive protein, rheumatoid factor and anti-cyclic citrullinated protein. Rheumatoid arthritis development was 19% in the waste water treatment plant workers with >10 working years and 8% for < 10 working years. Also, disease development started earlier (Age 30-40 years) among the waste water treatment plant workers compared to non waste water treatment plant workers (age: 40-50 years). Conclusions: Multiple exposures of waste water treatment plant workers to HAV might be one of the etiological stimuli of rheumatoid arthritis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
量子星尘发布了新的文献求助10
1秒前
Haha完成签到,获得积分20
2秒前
2秒前
Haha发布了新的文献求助10
7秒前
ovo发布了新的文献求助10
9秒前
量子星尘发布了新的文献求助10
10秒前
11秒前
haan发布了新的文献求助10
16秒前
雷锋完成签到,获得积分10
17秒前
24秒前
wawaaaah完成签到 ,获得积分10
25秒前
量子星尘发布了新的文献求助10
32秒前
33秒前
41秒前
共享精神应助Haha采纳,获得10
42秒前
43秒前
量子星尘发布了新的文献求助30
48秒前
50秒前
53秒前
量子星尘发布了新的文献求助10
56秒前
58秒前
yyy发布了新的文献求助10
58秒前
zz发布了新的文献求助10
1分钟前
烟花应助yyy采纳,获得10
1分钟前
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
领导范儿应助科研通管家采纳,获得10
1分钟前
ding应助科研通管家采纳,获得10
1分钟前
量子星尘发布了新的文献求助10
1分钟前
吾日三省吾身完成签到 ,获得积分10
1分钟前
852应助LINxu采纳,获得10
1分钟前
zz完成签到,获得积分20
1分钟前
1分钟前
1分钟前
金葡菌发布了新的文献求助30
1分钟前
ovo发布了新的文献求助10
1分钟前
FashionBoy应助满意谷波采纳,获得10
1分钟前
1分钟前
量子星尘发布了新的文献求助10
1分钟前
1分钟前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Neuromuscular and Electrodiagnostic Medicine Board Review 1000
Statistical Methods for the Social Sciences, Global Edition, 6th edition 600
こんなに痛いのにどうして「なんでもない」と医者にいわれてしまうのでしょうか 510
Walter Gilbert: Selected Works 500
An Annotated Checklist of Dinosaur Species by Continent 500
岡本唐貴自伝的回想画集 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3660936
求助须知:如何正确求助?哪些是违规求助? 3222150
关于积分的说明 9743712
捐赠科研通 2931683
什么是DOI,文献DOI怎么找? 1605151
邀请新用户注册赠送积分活动 757705
科研通“疑难数据库(出版商)”最低求助积分说明 734462