医学
荟萃分析
病态的
化疗
新辅助治疗
肿瘤科
内科学
癌症
外科
乳腺癌
作者
Zining Liu,Zhening Zhang,Hua Liu,Junbing Chen
出处
期刊:Future Oncology
[Future Medicine]
日期:2023-02-01
卷期号:19 (5): 397-408
标识
DOI:10.2217/fon-2022-1061
摘要
Aim: The authors conducted a meta-analysis to determine the association between time-to-surgery (TTS) after neoadjuvant chemotherapy and patient outcomes in locally advanced gastric cancer. Methods: Electronic databases were searched to identify potential studies, in which the authors compared patient outcomes between those with TTS within 4 (and 6) weeks of completion of neoadjuvant chemotherapy and those after 4 (and 6) weeks. Results: Six studies, including 1238 patients, were eligible for inclusion. Pooled data showed no significant differences in rates of pathological complete response, major pathological response, ypN0, complications, R0 resection and operative time between groups of longer TTS and shorter TTS. Conclusion: There was no statistically advantageous impact of prolonged TTS on pathological and surgical outcomes. Large, population-based studies are warranted.
科研通智能强力驱动
Strongly Powered by AbleSci AI