Bi‐tailed N‐cationic surfactant promoted green synthesis of 2‐amino‐5‐oxo‐4‐alkyl‐4,5‐dihydropyrano[3,2‐c]chromene‐3‐carbonitrile derivatives via multicomponent reaction

Abstract Diversely functionalized 2‐amino‐5‐oxo‐4‐alkyl‐4,5‐dihydropyrano[3,2‐c]chromene‐3‐carbonitrile derivatives were synthesized from substituted aromatic aldehydes, 4‐hydroxy coumarin and malononitrile using benzethonium chloride as an easily available, less explored green catalyst and 1:4 (EtOH:H 2 O) as a green solvent via multicomponent reaction. All the products were thoroughly characterized by infrared (IR), 1 H‐NMR, 13 C‐NMR, and mass spectral analyses. Synthesized compounds were screened rule of five for drug‐likeness and green matrix properties.