纳米医学
胶质母细胞瘤
药物输送
放射治疗
医学
血脑屏障
脑病
脑癌
脑瘤
机制(生物学)
疾病
中枢神经系统
神经科学
重症监护医学
内科学
纳米技术
病理
癌症
癌症研究
心理学
纳米颗粒
材料科学
哲学
认识论
作者
Xiaowei Song,Haisheng Qian,Yongqiang Yu
出处
期刊:Small
[Wiley]
日期:2023-07-07
卷期号:19 (45)
被引量:18
标识
DOI:10.1002/smll.202302613
摘要
Abstract Glioblastoma is one of the most aggressive central nervous system malignancies with high morbidity and mortality. Current clinical approaches, including surgical resection, radiotherapy, and chemotherapy, are limited by the difficulty of targeting brain lesions accurately, leading to disease recurrence and fatal outcomes. The lack of effective treatments has prompted researchers to continuously explore novel therapeutic strategies. In recent years, nanomedicine has made remarkable progress and expanded its application in brain drug delivery, providing a new treatment for brain tumors. Against this background, this article reviews the application and progress of nanomedicine delivery systems in brain tumors. In this paper, the mechanism of nanomaterials crossing the blood‐brain barrier is summarized. Furthermore, the specific application of nanotechnology in glioblastoma is discussed in depth.
科研通智能强力驱动
Strongly Powered by AbleSci AI