Development of a Scalable Process for an IL-17A Inhibitor LY3509754. Part II: Synthesis of the α-Bromoketone Intermediate Leveraging Concomitant Decarboxylation Following Enzymatic Ester Hydrolysis
脱羧
化学
酶
水解
组合化学
过程(计算)
有机化学
催化作用
计算机科学
操作系统
作者
Qiang Yang,Yu Lu,Thomas J. Beauchamp,Scott A. Frank,Xavier Ortiz-Medina,Jing Chen,Lixuan Liang,Xin Zhang,Ping Huang