医学
结节病
肺动脉高压
心脏病学
内科学
并发症
重症监护医学
作者
Laurent Savale,Peter Dorfmüller,Athénaïs Boucly,Xavier Jaïs,Thomas Lacoste-Palasset,Mitja Jevnikar,Andrei Seferian,Marc Humbert,Olivier Sitbon,David Montani
标识
DOI:10.1016/j.ccm.2023.08.007
摘要
Pulmonary hypertension is a life-threatening complication of advanced sarcoidosis . Many mechanisms can cause an elevation of pulmonary pressure in sarcoidosis, leading to precapillary or postcapillary pulmonary hypertension. Sarcoidosis-associated pulmonary hypertension contributes to severe exertional dyspnea, reduced exercise capacity, and notably compromised the survival. Despite the critical functional and prognostic implications of pulmonary hypertension in sarcoidosis, there is a scarcity of specific guidelines on the management of these patients due to a lack of evidence. Hence, further research is required to identify subgroups of patients who may benefit from pulmonary arterial hypertension-targeted therapies and/or immunosuppressive therapies .
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