An Experimental Laboratory Study Using the Miyake-Apple Posterior View Technique to Investigate the Dynamics Between Capsular Bags and Different IOL Models

To evaluate the dynamics between capsular bags and different intraocular lens (IOL) models in human cadaver eyes using the Miyake-Apple posterior view technique.In an in vitro laboratory study, human cadaver eyes were prepared according to the Miyake-Apple posterior view technique. Five IOLs from each of the six groups (Avansee 1P [Simonvision], Avansee 3P [Simonvision], CT Lucia [Carl Zeiss Meditec], Acrysof [Alcon Laboratories, Inc], RayOne [Rayner], and CT Asphina [Carl Zeiss Meditec]) were implanted into capsular bags with different diameters. The empty capsular bag diameter and capsular bag diameter with an IOL in it were evaluated based on the Miyake-Apple view pictures. Posterior capsule striae were observed and compared between groups. The arc of contact between IOLs and the capsular equator was noted. Correlations between the empty capsular bag diameter and the capsular bag diameter with IOL, as well as between the empty capsular bag diameter and the arc of contact, were examined. With the Avansee 3P as a reference, the area deviation of the haptics of IOL models with looped haptics was compared.The capsular bag diameter with IOL inside and the arc of contact were proportional to the empty capsular bag diameter. The RayOne, Avansee 3P, and CT Lucia showed a longer arc of contact. Posterior capsule striae were observed in the Avansee 1P (1, 20%), Avansee 3P (5, 100%), Acrysof (1, 20%), and RayOne (2, 40%). Areas of deviation were 0.38 mm2 (Avansee 1P), 0.24 mm2 (CT Lucia), 0.34 mm2 (Acrysof), and 0.31 mm2 (RayOne), respectively.Different IOL models showed varied characteristics in terms of capsular bag fitting and arc of contact. Understanding these dynamics is critical to optimizing postoperative outcomes. [J Refract Surg. 2022;38(10):654-660.].