[Role of oxidative stress in tissue remodeling of chronic rhinosinusitis].

Summary Chronic rhinosinusitis (CRS),one of the common diseases in otolaryngology,has become one of the major diseases affecting human health and the patients' quality of life in a severe degree.Many chronic airway inflammatory diseases are characterized by tissue remodeling,which has also been found playing an important role in the pathogenesis of CRS,and been affected by many factors.In this article,the role of oxidative stress and the interaction among TGF-β1 in tissue remodeling were summarized and analyzed,aming to provide a reference for clinical diagnosis and research of CRS.