Effect of Chilled Irrigation on Caliceal Fluid Temperature and Time to Thermal Injury Threshold During Laser Lithotripsy: In Vitro Model

医学 热电偶 灌溉 碎石术 激光器 核医学 生物医学工程 外科 材料科学 光学 复合材料 生态学 生物 物理
作者
Julie J. Dau,Timothy L. Hall,Adam D. Maxwell,Khurshid R. Ghani,William W. Roberts
出处
期刊:Journal of Endourology [Mary Ann Liebert, Inc.]
卷期号:35 (5): 700-705 被引量:20
标识
DOI:10.1089/end.2020.0896
摘要

Introduction: High-power lasers (100–120 W) have widely expanded the available settings for laser lithotripsy and facilitated tailoring of treatment for individual cases. Previous in vitro and in vivo studies have demonstrated that a toxic thermal dose to tissue can result from treatment within a renal calix. The objective of this in vitro study was to compare thermal dose and time with tissue injury threshold when using chilled (CH) irrigation and room temperature (RT) irrigation. Materials and Methods: A glass tube attached to a 19 mm diameter bulb simulating a renal calix was placed in a 37°C water bath. A 242 μm laser fiber was passed through a ureteroscope with its tip in the center of the glass bulb. A wire thermocouple was placed 3 mm proximal to the ureteroscope tip to measure caliceal fluid temperature. RT at 19°C or CH at 1°C irrigation was delivered at 0, 8, 12, 15, or 40 mL/minute. The laser was activated at 0.5 J × 80 Hz (40 W) for 60 seconds. Thermal dose was calculated using the Sapareto and Dewey t43 methodology with thermal dose = 120 equivalent minutes considered the threshold for thermal tissue injury. Results: At each irrigation rate, CH irrigation produced a lower starting temperature, a lower plateau temperature, and less thermal dose compared with RT irrigation. The threshold of thermal injury was reached after 13 seconds of laser activation without irrigation. With 12 mL/minute irrigation, the threshold was reached in 46 seconds with RT irrigation but was not reached with CH irrigation. Conclusion: As higher power laser lithotripsy techniques become further refined, methods to mitigate and control thermal dose are necessary to enhance efficiency. CH irrigation slows temperature rise, decreases plateau temperature, and lowers thermal dose during high-power laser lithotripsy.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李健的小迷弟应助良药采纳,获得10
刚刚
lw777发布了新的文献求助10
刚刚
肖肖发布了新的文献求助10
1秒前
2秒前
2秒前
卡萨卡萨完成签到,获得积分10
6秒前
青松果完成签到,获得积分10
8秒前
yousen完成签到,获得积分20
8秒前
Sid应助Sunwenrui采纳,获得60
8秒前
赘婿应助lw777采纳,获得10
10秒前
11秒前
小蘑菇应助张大英采纳,获得10
11秒前
华仔应助2889580752采纳,获得10
13秒前
嘻嘻完成签到,获得积分10
13秒前
14秒前
丘比特应助科研通管家采纳,获得10
14秒前
领导范儿应助科研通管家采纳,获得10
14秒前
慕青应助科研通管家采纳,获得10
14秒前
14秒前
斯文败类应助科研通管家采纳,获得10
14秒前
14秒前
思源应助科研通管家采纳,获得10
14秒前
田様应助科研通管家采纳,获得10
14秒前
Volcano完成签到,获得积分10
14秒前
无花果应助俏皮的白柏采纳,获得10
15秒前
单薄的夜南应助宁学者采纳,获得10
15秒前
16秒前
16秒前
16秒前
17秒前
空禅yew发布了新的文献求助10
17秒前
华仔应助云辞忧采纳,获得10
19秒前
19秒前
Sunwenrui完成签到,获得积分10
19秒前
12完成签到,获得积分10
21秒前
whoami发布了新的文献求助10
22秒前
22秒前
搜集达人应助TTT0530采纳,获得10
23秒前
张大英发布了新的文献求助10
24秒前
24秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3988868
求助须知:如何正确求助?哪些是违规求助? 3531255
关于积分的说明 11253071
捐赠科研通 3269858
什么是DOI,文献DOI怎么找? 1804822
邀请新用户注册赠送积分活动 881994
科研通“疑难数据库(出版商)”最低求助积分说明 809035