分散性
差示扫描量热法
抗氧化剂
傅里叶变换红外光谱
多酚
超声
化学
粒径
化学工程
纳米技术
核化学
色谱法
有机化学
材料科学
物理化学
工程类
物理
热力学
作者
Yue Sun,Jinpeng Chi,Xinqi Ye,Shuo Wang,Jin Liang,Pengxiang Yue,Hang Xiao,Xueling Gao
标识
DOI:10.1016/j.lwt.2020.110554
摘要
Anthocyanins (ACNs) are a series of polyphenols found in plants with various biological activities. To overcome their instability toward external environments and provide more effective encapsulation method, anthocyanins-loaded nanoliposomes (AN) were firstly prepared by combining ethanol injection method with ultrasonication. This method was simple and safe which avoiding organic solvents. Good physicochemical characterizations of AN (0.15% w/v ACNs) including the encapsulation efficiency (EE, 91.1 ± 1.7%), mean particle size (53.8 ± 1.8 nm), ζ-potential (−42.7 ± 2.2 mV) and polydispersity index (PDI, 0.19 ± 0.02) were observed. The encapsulation of AN was confirmed by transmission electron microscopy (TEM), differential scanning calorimetry (DSC) and fourier transform infrared (FTIR) spectroscopy. Nanoliposome encapsulation also enhanced the stability, cellular uptake and antioxidant activities of ACNs in vitro. It was demonstrated that the nanoliposomes prepared by this method were an efficient carriers for the delivery of ACNs, and the results expects to provide theories and practice guides for further applications of AN.
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