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A Rapid Method to Preoperatively Assess Frailty for Older Patients with Pelvic Floor Conditions

医学 盆底 盆底疾病 外科
作者
Katherine Amin,Wai Lee,Dena Moskowitz,Kathleen C. Kobashi,Alvaro Lucioni,May J. Reed,Michael G. Nash,Una Lee
出处
期刊:The Journal of Urology [Lippincott Williams & Wilkins]
卷期号:203 (6): 1172-1177 被引量:9
标识
DOI:10.1097/ju.0000000000000739
摘要

No AccessJournal of UrologyAdult Urology1 Jun 2020A Rapid Method to Preoperatively Assess Frailty for Older Patients with Pelvic Floor Conditions Katherine A. Amin, Wai Lee, Dena Moskowitz, Kathleen C. Kobashi, Alvaro Lucioni, May J. Reed, Michael Nash, and Una J. Lee Katherine A. AminKatherine A. Amin *Correspondence: Department of Urology, Professional Arts Center, 1150 NW 14th St., Suite 309, Miami, Florida 33136 telephone: 305-243-6090; FAX: 305-243-6597; E-mail Address: [email protected] Department of Urology, University of Miami Miller School of Medicine, Miami, Florida , Wai LeeWai Lee Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington , Dena MoskowitzDena Moskowitz Department of Urology, University of California, Irvine, Irvine, California , Kathleen C. KobashiKathleen C. Kobashi Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington , Alvaro LucioniAlvaro Lucioni Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington , May J. ReedMay J. Reed Division of Gerentology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington , Michael NashMichael Nash Department of Statistics, University of Washington, Seattle, Washington , and Una J. LeeUna J. Lee Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington View All Author Informationhttps://doi.org/10.1097/JU.0000000000000739AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Assessment of frailty can help surgeons predict perioperative risk and guide preoperative counseling. However, current methods are often cumbersome in the clinical setting. We prospectively compared the effectiveness of a rapid picture based Clinical Frailty Scale (CFS-9) assessed by patient and surgeon against reference standard Fried Frailty Index in older patients with pelvic floor conditions. Materials and Methods: We enrolled 71 patients between March 2018 and June 2019. Frailty assessment using CFS-9 (scale ranging from very fit to terminally ill) was performed followed by the Fried Frailty Index, a validated tool of 5 measures (shrinking, physical energy, activity, grip strength, walking speed). Correlations and agreement between Fried Frailty Index and CFS-9 scores from the treating surgeon, a second surgeon (surgeon 2) and patient were analyzed using sensitivity, specificity, area under the curve and Cohen's Kappa. Results: The patient cohort was mostly female (97.2%), with a mean age (±SD) of 73.0 (±5.9) years and 23.9% were frail using the Fried Frailty Index. Compared to the Fried Frailty Index, CFS-9 scores of the treating surgeon, surgeon 2 and patient had AUC values (95% CI) of 0.86 (0.77–0.86), 0.91 (0.84–0.91) and 0.88 (0.79–0.88), respectively. As assessed by Cohen's Kappa the CFS-9 scores all had substantial (surgeon 2, Kappa 0.66, 95% CI 0.46—0.85 or moderate (all other CFS-9 measures, Kappa 0.44 to 0.58) agreement with the Fried Frailty Index scores. Conclusions: Rapid and effective validated tools to screen for frailty are needed in the clinical setting. CFS-9 is an excellent predictor of frailty compared to the Fried Frailty Index for patients with pelvic floor conditions. References 1. : Forecasting the prevalence of pelvic floor disorders in U.S. women: 2010 to 2050. Obstet Gynecol 2009; 114: 1278. Google Scholar 2. : Epidemiology and prevalence of pelvic organ prolapse. Curr Opin Urol 2013; 23: 293. Google Scholar 3. : Defining overactive bladder: epidemiology and burden of disease. Urology 2004; 64: 2. Google Scholar 4. : The impact of urinary urgency and frequency on health-related quality of life in overactive bladder: results from a national community survey. Value Health 2004; 7: 455. Google Scholar 5. : Comorbidities associated with overactive bladder. Am J Manag Care, suppl., 2000; 6: S574. Google Scholar 6. : Urgency and urge incontinence in an older population: ten-year changes and their association with mortality. Aging Clin Exp Res 2002; 14: 412. Google Scholar 7. ; Cardiovascular Health Study Collaborative Research Group: Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146. Google Scholar 8. : Frailty in elderly people. Lancet 2013; 381: 752. Google Scholar 9. : Impact of frailty on complications in patients undergoing common urological procedures: a study from the American College of Surgeons National Surgical Quality Improvement database. BJU Int 2016; 117: 836. Google Scholar 10. : Too frail for surgery? Initial results of a large multidisciplinary prospective study examining preoperative variables predictive of poor surgical outcomes. J Am Coll Surg 2013; 217: 665. Google Scholar 11. : Preoperative frailty is associated with discharge to skilled or assisted living facilities after urologic procedures of varying complexity. Urology 2016; 97: 25. Google Scholar 12. : Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg 2012; 215: 453. Google Scholar 13. : A global clinical measure of fitness and frailty in elderly people. CMAJ 2005; 173: 489. Google Scholar 14. : Defining frailty in research abstracts: a systematic review and recommendations for standardization. J Frailty Aging 2019; 8: 67. Google Scholar 15. : Frailty and lower urinary tract symptoms. Curr Urol Rep 2017; 18: 67. Google Scholar 16. : Overactive bladder is strongly associated with frailty in older individuals. Urology 2017; 106: 26. Google Scholar 17. : Frailty and the role of obliterative versus reconstructive surgery for pelvic organ prolapse: a national study. J Urol 2017; 197: 1502. Link, Google Scholar 18. : Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg 2010; 210: 901. Google Scholar 19. : Grip strength as a frailty diagnostic component in geriatric inpatients. Clin Interv Aging 2017; 12: 1151. Google Scholar 20. : The timed up and go test as a measure of frailty in urologic practice. Urology 2017; 106: 32. Google Scholar 21. : Fried frailty phenotype assessment components as applied to geriatric inpatients. Clin Interv Aging 2016; 11: 453. Google Scholar 22. : Rapid methods for routine frailty assessment during vascular surgery clinic visits. Ann Vasc Surg 2018; 46: 134. Google Scholar 23. : Comparison of bedside screening methods for frailty assessment in older adult trauma patients in the emergency department. Am J Emerg Med 2019; 37: 12. Google Scholar 24. : Clinical frailty scale in an acute medicine unit: a simple tool that predicts length of stay. Can Geriatr J 2016; 19: 34. Google Scholar 25. : A coefficient of agreement for nominal scales. Educ Psychol Meas 1960; 20: 37. Crossref, Google Scholar 26. : Frailty as a predictor of complications after radical cystectomy: a prospective study of various preoperative assessments. Urol Oncol 2019; 37: 40. Google Scholar 27. : The impact of frailty on artificial urinary sphincter placement and removal procedures. Urology 2019; 129: 210. Google Scholar 28. : Frailty, cognitive impairment, and functional disability in older women with female pelvic floor dysfunction. Int Urogynecol J 2015; 26: 823. Google Scholar No direct or indirect commercial, personal, academic, political, religious or ethical incentive is associated with publishing this article. © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byGomelsky A (2020) Editorial CommentJournal of Urology, VOL. 205, NO. 1, (197-197), Online publication date: 1-Jan-2021. Volume 203Issue 6June 2020Page: 1172-1177Supplementary Materials Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.Keywordsfrailtytreatment outcomeoperativesurgical proceduresprolapseurinary incontinenceMetricsAuthor Information Katherine A. Amin Department of Urology, University of Miami Miller School of Medicine, Miami, Florida *Correspondence: Department of Urology, Professional Arts Center, 1150 NW 14th St., Suite 309, Miami, Florida 33136 telephone: 305-243-6090; FAX: 305-243-6597; E-mail Address: [email protected] More articles by this author Wai Lee Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington More articles by this author Dena Moskowitz Department of Urology, University of California, Irvine, Irvine, California More articles by this author Kathleen C. Kobashi Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington More articles by this author Alvaro Lucioni Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington More articles by this author May J. Reed Division of Gerentology and Geriatric Medicine, Department of Medicine, University of Washington, Seattle, Washington More articles by this author Michael Nash Department of Statistics, University of Washington, Seattle, Washington More articles by this author Una J. Lee Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington Financial interest and/or other relationship with Medtronic. More articles by this author Expand All No direct or indirect commercial, personal, academic, political, religious or ethical incentive is associated with publishing this article. Advertisement PDF downloadLoading ...

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