Apparent Diffusion Coefficient (ADC) Differentiates Retinoblastoma from Coats Disease on MRI

Coats' disease can be difficult to differentiate from retinoblastoma. While MR imaging of retinoblastoma and Coats' disease have been examined for differentiating features such as eye size, vitreous seeding, and shape of retinal detachment, there is a lack of data on apparent diffusion coefficient (ADC). ADC is a measure of the diffusion (of water molecules) within tissue, and is commonly clinically calculated using MRI DESIGN: Retrospective cross-sectional study METHODS: Patient or study population: Children <18 diagnosed with Coats disease or Retinoblastoma between 1/1/2018-8/1/2022 who had MRI imaging that was reviewable.