医学
外体
微泡
干细胞
干细胞疗法
心功能曲线
心肌梗塞
离体
收缩性
祖细胞
心脏病学
心力衰竭
内科学
细胞生物学
病理
体内
生物
间充质干细胞
生物化学
基因
小RNA
生物技术
作者
Junlang Li,Shenghuan Sun,Dashuai Zhu,Xuan Mei,Yongbo Lyu,Ke Huang,Yuan Li,Shuo Liu,Zhenzhen Wang,Shiqi Hu,Halle Lutz,Kristen D. Popowski,Phuong‐Uyen Dinh,Atul J. Butte,Ke Cheng
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2024-08-26
卷期号:150 (9): 710-723
被引量:19
标识
DOI:10.1161/circulationaha.123.065005
摘要
Exosome therapy shows potential for cardiac repair after injury. However, intrinsic challenges such as short half-life and lack of clear targets hinder the clinical feasibility. Here, we report a noninvasive and repeatable method for exosome delivery through inhalation after myocardial infarction (MI), which we called stem cell-derived exosome nebulization therapy (SCENT).
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