生物
旁分泌信号
肥大细胞
细胞生物学
桅杆（植物学）
过敏反应
脂质信号
细胞
免疫学
炎症
生物化学
受体
过敏
作者
Yoshitaka Taketomi,Takayoshi Higashi,Kuniyuki Kano,Yoshimi Miki,Chika Mochizuki,Shota Toyoshima,Yoshimichi Okayama,Yasumasa Nishito,Susumu Nakae,Satoshi Tanaka,Suzumi M. Tokuoka,Yoshiya Oda,Shigeyuki Shichino,Satoshi Ueha,Kouji Matsushima,Noriyuki Akahoshi,Satoshi Ishii,Jerold Chun,Junken Aoki,Makoto Murakami
出处
期刊：Immunity
[Cell Press]
日期：2024-07-12
卷期号：57 (8): 1828-1847.e11
被引量：3
标识
DOI：10.1016/j.immuni.2024.06.012
摘要
Interaction of mast cells (MCs) with fibroblasts is essential for MC maturation within tissue microenvironments, although the underlying mechanism is incompletely understood. Through a phenotypic screening of >30 mouse lines deficient in lipid-related genes, we found that deletion of the lysophosphatidic acid (LPA) receptor LPA
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