酿酒酵母
结直肠癌
纳米-
输送系统
遗传增强
癌症治疗
纳米技术
基因传递
癌症
材料科学
基因
癌症研究
医学
生物信息学
药理学
化学
生物
内科学
生物化学
复合材料
作者
Tianli Shen,Xuejun Sun,Jing Wang,Wei Wang,Zilu Chen,Yuyao Lin,Sihua Li,Peng Hang,Lizhong Zeng,Li Gan,Xuqi Li,Bo Wang,Jingya Ning,Haimei Wen,Bo Lei,Long Zhang
出处
期刊:ACS Nano
[American Chemical Society]
日期:2024-10-03
标识
DOI:10.1021/acsnano.4c08044
摘要
The efficient delivery of RNA-based drugs to solid tumors remains a formidable obstacle. We aim to develop a safe and efficient oral drug delivery system compatible with RNA-based drugs that is urgently needed to overcome challenges such as enzymatic degradation and gastrointestinal barriers to facilitate effective treatment for treating colorectal cancer (CRC). To address these challenges, we utilized engineered modified
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