噻唑
癌症
化学
药品
组合化学
药理学
医学
生物
立体化学
内科学
作者
Vikas Sharma,Balwinder Kaur,Gurdeep Singh,Iqubal Singh
出处
期刊:Anti-cancer Agents in Medicinal Chemistry
[Bentham Science]
日期:2022-12-22
卷期号:23 (8): 869-881
被引量:10
标识
DOI:10.2174/1871520623666221221143918
摘要
After cardiovascular disease, cancer is the most common cause of death worldwide. Due to their versatility, heterocyclic compounds play an important role in drug discovery. Medical remedies are constantly being discovered, especially for catastrophic disorders such as cancer. Here, this review is focused on sulphur containing heterocyclic compounds as anticancer agents. Sulphur is found in a variety of vitamin cofactors, sugars, and nucleic acids, and it also plays a function in controlling translation by sulphurating transfer RNA. Sulphur has obtained a lot of interest in the anticancer research medicinal fields. Thiophene derivatives were tested for anti-proliferative activity against breast cancer cells in a recent screening study, and the bulk of chemicals exhibited potent inhibitory effects. In recent years, azoles such as thiazole and thiadiazole structures have gained prominence in cancer research.
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