生物
石碑
转录因子
重编程
细胞生物学
拟南芥
内胚层
突变体
抄写(语言学)
侧根
植物
激酶
细胞
生物化学
基因
哲学
语言学
作者
Xiao Hui-xin,Yumei Hu,Yaping Wang,Jinkui Cheng,Jinyi Wang,Guojingwei Chen,Qian Li,Shuwei Wang,Y. Wang,Shaoshuai Wang,Yi Wang,Wei Xuan,Zhen Li,Yan Guo,Zhizhong Gong,Jiřı́ Friml,Jing Zhang
标识
DOI:10.1016/j.devcel.2022.11.006
摘要
Plant root architecture flexibly adapts to changing nitrate (NO3−) availability in the soil; however, the underlying molecular mechanism of this adaptive development remains under-studied. To explore the regulation of NO3−-mediated root growth, we screened for low-nitrate-resistant mutant (lonr) and identified mutants that were defective in the NAC transcription factor NAC075 (lonr1) as being less sensitive to low NO3− in terms of primary root growth. We show that NAC075 is a mobile transcription factor relocating from the root stele tissues to the endodermis based on NO3− availability. Under low-NO3− availability, the kinase CBL-interacting protein kinase 1 (CIPK1) is activated, and it phosphorylates NAC075, restricting its movement from the stele, which leads to the transcriptional regulation of downstream target WRKY53, consequently leading to adapted root architecture. Our work thus identifies an adaptive mechanism involving translocation of transcription factor based on nutrient availability and leading to cell-specific reprogramming of plant root growth.
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