癌症
癌症治疗
纳米材料
癌症研究
化学
医学
纳米技术
材料科学
内科学
作者
Dhelal F Mohammed,Hussein Ali Madlool,Mohammed Faris,Bashar Hadi Shalan,Huda Hadi Hasan,Nidaa F Azeez,Fatima Hashim Abbas
出处
期刊:Nanomedicine
[Future Medicine]
日期:2022-10-01
卷期号:17 (24): 1891-1906
被引量:7
标识
DOI:10.2217/nnm-2022-0187
摘要
The most important aspect of chemodynamic therapy (CDT) is the harnessing of Fenton or Fenton-like chemistry for cancer therapy within the tumor microenvironment, which occurs because of the moderate acidity and overexpressed H2O2 in the tumor microenvironment. Hydroxyl radicals (•OH) produced within tumor cells via Fenton and Fenton-like reactions cause cancer cell death. Reactive oxygen species-mediated CDT demonstrates a desired anticancer impact without the need for external stimulation or the development of drug resistance. Cancer therapy based on CDT is known as a viable cancer therapy modality. This review discusses the most recent CDT advancements and provides some typical instances. As a result, potential methods for further improving CDT efficiency under the guidance of Fenton chemistry are offered.
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