A Comprehensive Review on Novel Polymer Biomaterials for Hydrogel-Based Drug Delivery System

Abstract: Hydrogel biomaterials, which are formed from polymers generated from either natural or synthetic sources, are characterized by their mechanical stability as well as their biological acceptability. Hydrogels are characterized by properties such as a high swelling index, biocompatibility, the ability to be easily manipulated, flexibility, and rapid degradation. Hydrogels are commonly used as drug carriers due to the fact that they are simple to produce and may be applied by themselves. Using hydrogels in drug delivery applications, where gel-based nanocarriers carry drug molecules to the area of interest in living tissues. The research community is interested in doing this because of the unique physical and chemical properties that hydrogels possess. It has been discussed that several new hydrogel-based solutions are being employed for the administration of drugs that are not taken orally. Hydrogel systems can be developed for use in either passive or active drug administration, making them suitable for a broad variety of settings and applications. In addition to possessing essential biocompatible properties, hydrogels are able to move freely within the human body without having any visible impact on the surrounding environment. The present review has been developed to examine novel concepts linked to hydrogels and their delivery mechanism. This is due to the fact that hydrogels possess qualities that are both unique and novel. In this article, the mechanics of drug delivery systems that are based on hydrogels are detailed. These processes include loading, releasing, and targeting. For these components, the development and investigation of cutting-edge hydrogel- based delivery systems is necessary.