Which One Is the Best for Living Donation: A Multiple-Artery Left Kidney Nephrectomy or a Right Kidney Nephrectomy?

医学 肾切除术 肾移植 急性肾小管坏死 肾静脉 肾动脉 肾静脉血栓形成 肾功能 外科 血栓形成 移植 静脉 肌酐 入射(几何) 泌尿科 内科学 物理 光学
作者
Diogo Nunes‐Carneiro,André Marques-Pinto,Carlos Veiga,Isaac Braga,João Cabral,Manuela Almeida,Vítor Cavadas,António Castro-Henriques,Rui Almeida,Avelino Fraga,Miguel Silva-Ramos
出处
期刊:Transplantation Proceedings [Elsevier BV]
卷期号:51 (5): 1559-1562 被引量:8
标识
DOI:10.1016/j.transproceed.2019.01.045
摘要

The current approach in living-donor kidney transplant is to preserve the best kidney for the donor and harvest the contralateral one. Due to a shorter renal vein and a greater incidence of venous thrombosis, left kidneys are more frequently elected. Notwithstanding, arterial anatomy may be complex and thus render the transplantation procedure more difficult and prone to complications.To analyze the outcomes after multiple-artery left kidney nephrectomy (MALKN) and right kidney nephrectomy (RKN).Seventy-three cases were performed from 1999 to 2017 in our institution: 34 MALKN and 39 RKN. The mean operative time was significantly longer in MALKN. Warm ischemia time, donor and receptor hospital stay, and postoperative complications did not differ between groups. There was a positive correlation between renal arteries' ostia distance in MALKN and the duration of warm ischemia period. There was no significant difference in the incidence of acute tubular necrosis, first-year variations in serum creatinine, and glomerular filtration rate between groups. Long-term graft survival did not significantly differ between groups. Three cases of vein thrombosis after RKN were reported with graft loss.The safety and efficacy of MALKN does not differ from RKN, although there appears to be a higher incidence of vein thrombosis after right kidney transplantation. Despite being technically more demanding, particularly in cases with distant artery ostia, MALKN could be a better option than RKN for living donation, expanding the available donor pool, although more studies are needed to affirm this conclusion.

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