Cartilage Lesions and the Development of Osteoarthritis After Internal Fixation of Ankle Fractures

医学 骨关节炎 优势比 脚踝 置信区间 软骨 外科 射线照相术 关节镜检查 内科学 解剖 病理 替代医学
作者
Sjoerd A.S. Stufkens,Markus Knupp,Monika Horisberger,C. Lampert,Beat Hintermann
出处
期刊:Journal of Bone and Joint Surgery, American Volume [Wolters Kluwer]
卷期号:92 (2): 279-286 被引量:151
标识
DOI:10.2106/jbjs.h.01635
摘要

Background: The role of the location and severity of the initial cartilage lesions associated with an ankle fracture in the development of posttraumatic osteoarthritis has not been established, to our knowledge. Methods: We performed a long-term follow-up study of a consecutive, prospectively included cohort of 288 ankle fractures that were treated operatively between June 1993 and November 1997. Arthroscopy had been performed in all cases in order to classify the extent and location of cartilage damage. One hundred and nine patients (47%) were available for follow-up after a mean of 12.9 years. The main outcome parameters were the American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score for clinical evaluation and a modified Kannus osteoarthritis score for radiographic assessment of the development of posttraumatic osteoarthritis. Results: Cartilage damage anywhere in the ankle joint was associated with a suboptimal clinical outcome (odds ratio, 5.0 [95% confidence interval = 1.3 to 20.1]; p = 0.02) and with a suboptimal radiographic outcome (odds ratio = 3.4 [95% confidence interval = 1.0 to 11.2]; p = 0.04). An association was also found between the development of clinical signs of osteoarthritis and a deep lesion (>50% of the cartilage thickness) on the anterior aspect of the talus (odds ratio = 12.3 [95% confidence interval = 1.4 to 108.0]; p = 0.02) and a deep lesion on the lateral aspect of the talus (odds ratio = 5.4 [95% confidence interval = 1.2 to 23.5]; p = 0.02). A deep lesion on the medial malleolus was associated with the development of clinical signs of osteoarthritis (odds ratio = 5.2 [95% confidence interval = 1.9 to 14.6]; p < 0.01) and radiographic signs of osteoarthritis (odds ratio = 2.9 [95% confidence interval = 1.1 to 7.9]; p = 0.03) of osteoarthritis. There was no significant correlation between cartilage lesions on the fibula and the long-term outcome. Conclusions: Our findings show that initial cartilage damage seen arthroscopically following an ankle fracture is an independent predictor of the development of posttraumatic osteoarthritis. Specifically, lesions on the anterior and lateral aspects of the talus and on the medial malleolus correlate with an unfavorable clinical outcome. Level of Evidence: Prognostic Level II. See Instructions to Authors for a complete description of levels of evidence.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
yuncong323完成签到,获得积分10
2秒前
huohuo完成签到,获得积分10
4秒前
CB完成签到,获得积分10
5秒前
5秒前
6秒前
儒雅路人完成签到,获得积分10
7秒前
OLDBLOW完成签到,获得积分10
8秒前
8秒前
liupangzi完成签到,获得积分10
8秒前
wang完成签到,获得积分10
8秒前
9秒前
Catherkk发布了新的文献求助10
9秒前
lcdamoy完成签到,获得积分10
10秒前
钱浩然发布了新的文献求助10
10秒前
烊烊发布了新的文献求助10
11秒前
十曰完成签到,获得积分10
16秒前
jjjjchou完成签到,获得积分10
17秒前
虚心的不二完成签到 ,获得积分10
19秒前
xuzj应助科研通管家采纳,获得10
20秒前
小马甲应助科研通管家采纳,获得10
20秒前
20秒前
思源应助科研通管家采纳,获得10
20秒前
20秒前
研友_VZG7GZ应助科研通管家采纳,获得10
20秒前
fang应助科研通管家采纳,获得10
20秒前
隐形曼青应助科研通管家采纳,获得10
20秒前
科研通AI5应助科研通管家采纳,获得10
20秒前
FashionBoy应助科研通管家采纳,获得10
20秒前
shiizii应助科研通管家采纳,获得10
20秒前
22秒前
火星上的雨莲完成签到,获得积分10
26秒前
开朗的绮山发布了新的文献求助150
26秒前
平淡远山发布了新的文献求助10
27秒前
热心市民小红花应助Roman采纳,获得10
28秒前
艺术家完成签到 ,获得积分10
29秒前
研友_ngqjz8完成签到,获得积分10
30秒前
LT完成签到 ,获得积分0
31秒前
优秀的dd完成签到 ,获得积分10
32秒前
JamesPei应助八月宁静采纳,获得10
32秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038235
求助须知:如何正确求助?哪些是违规求助? 3575992
关于积分的说明 11374009
捐赠科研通 3305760
什么是DOI,文献DOI怎么找? 1819276
邀请新用户注册赠送积分活动 892662
科研通“疑难数据库(出版商)”最低求助积分说明 815022