Recent Updates on the Systemic and Local Safety of Intranasal Steroids

Background: Allergic rhinitis is a global health problem, and its prevalence rate and socioeconomic burden continue to increase. Intranasal steroid (INS) is the first treatment choice in the majority of patients, because of its ability to effectively control allergic symptoms. However, patients and clinicians are concerned about the potential adverse effects of prolonged INS use. Keywords: Adverse effects, allergic rhinitis, biological availability, epistaxis, intranasal administration, steroids.