Computed tomography-based acute stroke lesion timing and patient stratification

Minnerup and co-workers proposed a computed tomography (CT) -based procedure to determine age of acute/hyperacute stroke to aid patient stratification for reperfusion therapy 1 .The CT procedure converts Hounsfield Units (HU) determined in the stroke lesion into net water uptake due to ischaemia.There are issues in the paper that deserve attention.First,