髓内棒
医学
多骨性纤维发育不良
外科
股骨
纤维发育不良
截骨术
胫骨
骨科手术
作者
Giulio Gorgolini,Kristian Efremov,Fernando De Maio,Vito Potenza,Roberto Caterini,Ernesto Ippolito,Pasquale Farsetti
出处
期刊:Journal of Biological Regulators and Homeostatic Agents
日期:2020-05-01
卷期号:34: 47-52
被引量:3
摘要
Polyostotic fibrous dysplasia (PFD) generally cause deformities and fractures of femur and tibia and surgery is often required. The current surgical treatment for deformities is based on single or multiple osteotomies followed by stabilization with intramedullary nails, which are commonly used also for fractures. One of the most common surgical complications of intramedullary nailing is represented by surgical site infection with possible extension to the whole skeletal segment. In the present study we evaluated the incidence of surgical site infections in 44 patients affected by PFD in which 91 femurs or tibiae underwent intramedullary nailing to treat deformities or fractures. We never observed any infection of the operated femurs or tibiae until the final follow-up. The only post surgical infection was present in a patient with monomelic involvement at the contralateral non affected limb, which was surgically treated for limb length inequality, by femur shortening osteotomy stabilized by an intramedullary nail. The most likely hypothesis to explain the complete absence of infections in these patients may be related to the high local concentration of prophylactic antibiotic in the highly vascularized fibrodysplastic bone.
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