Acute Effects of Parent Stimulant Medication Versus Behavioral Parent Training on Mothers’ ADHD, Parenting Behavior, and At-Risk Children

心理学 评定量表 兴奋剂 家长培训 注意缺陷多动障碍 临床心理学 心理干预 干预(咨询) 精神科 发展心理学
作者
Andrea Chronis‐Tuscano,William P. French,Jennifer Strickland,Tyler Sasser,Erin N. Schoenfelder,Kathryn B. Whitlock,Mark A. Stein
出处
期刊:The Journal of Clinical Psychiatry [Physicians Postgraduate Press, Inc.]
卷期号:81 (5) 被引量:5
标识
DOI:10.4088/jcp.19m13173
摘要

Article Abstract Background: Attention-deficit/hyperactivity disorder (ADHD) is present in 25%-50% of parents of children with ADHD, compromising parenting and child behavioral treatment. Efforts to treat multiplex ADHD families have not compared behavioral parenting interventions to parent psychopharmacology without confounds of other treatments. This report describes a pilot early intervention study directly comparing parent lisdexamfetamine dimesylate (LDX) to behavioral parent training (BPT) in families in which the mother had currently untreated ADHD and the young child displayed ADHD symptoms. Methods: Mothers with ADHD (N = 35) of 4- to 8-year-old stimulant-naive children (N = 35) were randomly assigned to an 8-week trial of LDX (starting at 20 mg/d and titrated to a maximum of 70 mg/d) or BPT. Outcomes included multi-method, multi-informant measures of (1) maternal ADHD symptoms (Conners†Adult ADHD Rating Scales) and impairment (Clinical Global Impressions-Severity of Illness scale and CGI-Improvement scale ), (2) parenting (Alabama Parenting Questionnaire and Dyadic Parent-Child Interaction Coding System, Fourth Edition), and (3) child ADHD symptoms (Conners Parent Rating Scale Revised-Short Form and Conners Early Childhood Scale) and impairment (CGI-S, CGI-I, and Child Impairment Rating Scale). Results: At 8 weeks, both treatments improved mothers†self-reported emotion regulation and mothers†functioning on the CGI, but only LDX improved mothers†self-reported core ADHD symptoms. LDX was associated with improvement in parents†perception of their own ADHD symptoms (Conners Inattention and ADHD Index scores ) and their child's ADHD symptoms (P=.009). Fifty-six percent of the mothers treated with LDX (n=10) were "much" or "very much" improved with regard to their adult ADHD based on the CGI-I scores versus 6% of mothers receiving BPT (n=1; P=.003). BPT improved parenting on self-reported positive parenting (P=.007), inconsistent discipline (P>.0001), and corporal punishment (P=.001), while LDX improved reported inconsistent discipline (P=.001) and corporal punishment (P=.04) on the APQ, consistent with prior research. In contrast to parental LDX, which did not improve observed parenting, BPT was associated with increased positive parenting during child-directed play (P=.0002) and clean-up (P=.04) and less negative parenting (P=.04) during child-directed play. Six percent of children (n=1) whose mothers were randomized to LDX (n=18) were "much" or "very much" improved on the CGI-I compared to 35% (n=16) of those treated with BPT (P=.04). Conclusions: LDX and BPT each had unique effects on maternal ADHD symptoms and parenting, but modest effects on at-risk children. In general, LDX was more effective at treating mothers†core ADHD symptoms, but both LDX and BPT improved mothers†emotion regulation, and BPT resulted in more consistent effects on parenting measures via both maternal report and direct observation. As most children remained significantly impaired after 8 weeks of unimodal treatment, combination treatment and/or longer treatment duration may be necessary to improve functioning of multiplex ADHD families. Trial Registration: ClinicalTrials.gov identifier: NCT01816074
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
优雅的平安完成签到 ,获得积分10
5秒前
南浔完成签到 ,获得积分10
6秒前
zzx完成签到 ,获得积分10
7秒前
虚心的幻梅完成签到 ,获得积分10
8秒前
欧皇发布了新的文献求助50
8秒前
量子星尘发布了新的文献求助10
11秒前
Jasper应助科研通管家采纳,获得10
11秒前
勤恳的书文完成签到 ,获得积分10
12秒前
无敌大流流完成签到,获得积分10
13秒前
无辜凝天完成签到,获得积分10
16秒前
秋思冬念完成签到 ,获得积分10
18秒前
19秒前
ioio完成签到 ,获得积分10
20秒前
清爽的火车完成签到 ,获得积分10
22秒前
MRQ完成签到 ,获得积分10
25秒前
hyd1640完成签到,获得积分10
26秒前
金枪鱼子完成签到,获得积分10
26秒前
默默完成签到 ,获得积分10
31秒前
聪明勇敢有力气完成签到 ,获得积分10
32秒前
金枪鱼子发布了新的文献求助10
33秒前
buerzi完成签到,获得积分10
34秒前
leo完成签到,获得积分10
35秒前
35秒前
dldldl完成签到,获得积分10
37秒前
爱书儿的小周完成签到,获得积分10
38秒前
Noah完成签到 ,获得积分0
40秒前
小伊001完成签到,获得积分10
42秒前
欧皇完成签到,获得积分20
42秒前
心心完成签到 ,获得积分10
49秒前
量子星尘发布了新的文献求助10
50秒前
娇娇大王完成签到,获得积分10
53秒前
woshiwuziq完成签到 ,获得积分10
53秒前
自然白秋完成签到,获得积分20
54秒前
韦老虎完成签到,获得积分20
56秒前
自然白秋发布了新的文献求助20
58秒前
Krim完成签到 ,获得积分10
1分钟前
大个应助金枪鱼子采纳,获得10
1分钟前
喜悦向日葵完成签到 ,获得积分10
1分钟前
淡然的糖豆完成签到 ,获得积分10
1分钟前
E0702完成签到,获得积分10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
A new approach to the extrapolation of accelerated life test data 1000
Coking simulation aids on-stream time 450
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
Novel Preparation of Chitin Nanocrystals by H2SO4 and H3PO4 Hydrolysis Followed by High-Pressure Water Jet Treatments 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4015585
求助须知:如何正确求助?哪些是违规求助? 3555572
关于积分的说明 11318138
捐赠科研通 3288762
什么是DOI,文献DOI怎么找? 1812284
邀请新用户注册赠送积分活动 887882
科研通“疑难数据库(出版商)”最低求助积分说明 812015