Relationship between visceral adiposity index and male infertility

AndrologiaVolume 52, Issue 4 e13548 ORIGINAL ARTICLE Relationship between visceral adiposity index and male infertility Elif Turan, Elif Turan orcid.org/0000-0002-8228-6932 Department of Endocrinology and Metabolic Disease, Faculty of Medicine, Yozgat Bozok University, Yozgat, TurkeySearch for more papers by this authorÜnal Öztekin, Corresponding Author Ünal Öztekin dr_unal@hotmail.com orcid.org/0000-0001-9568-9442 Department of Urology, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey Correspondence Ünal Öztekin, Department of Urology, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey. Email: dr_unal@hotmail.comSearch for more papers by this author Elif Turan, Elif Turan orcid.org/0000-0002-8228-6932 Department of Endocrinology and Metabolic Disease, Faculty of Medicine, Yozgat Bozok University, Yozgat, TurkeySearch for more papers by this authorÜnal Öztekin, Corresponding Author Ünal Öztekin dr_unal@hotmail.com orcid.org/0000-0001-9568-9442 Department of Urology, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey Correspondence Ünal Öztekin, Department of Urology, Faculty of Medicine, Yozgat Bozok University, Yozgat, Turkey. Email: dr_unal@hotmail.comSearch for more papers by this author First published: 26 February 2020 https://doi.org/10.1111/and.13548Citations: 6Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract The visceral adiposity index (VAI), which is calculated by using parameters such as body mass index (BMI), waist circumference, triglyceride, and high-density lipoprotein cholesterol, has been reported to be associated with visceral fat distribution and increased cardiometabolic risk. We aimed to investigate the relationship between the VAI and hormone profiles as well as semen analysis in male infertility. This retrospective study included 278 adult men that were admitted to the urology and endocrine outpatient clinics. Patient data were reviewed, and outcomes were recorded. BMI and VAI were calculated and noted separately. BMI was negatively correlated with serum testosterone and testosterone/ estradiol ratio (T/E2) (p < .05 for all). There was no significant relationship between BMI and semen parameters (p > .05 for all). However, there was a significant negative correlation between VAI and semen parameters, total serum testosterone and T/E2 (p < .05 for all). Furthermore, VAI was independently associated with the total motility score. The increase in visceral adiposity that can be demonstrated by VAI may adversely affect male fertility due to its metabolic and hormonal effects. Since infertility occurs as a result of different metabolic conditions, the underlying mechanisms can be better understood from a multidisciplinary perspective. Citing Literature Volume52, Issue4May 2020e13548 RelatedInformation