紧密连接
细胞生物学
势垒函数
封堵器
上皮
化学
生物
功能(生物学)
信号转导
遗传学
作者
Paula Marincola Smith,Yash A. Choksi,Nicholas O. Markham,David N. Hanna,Jinghuan Zi,Connie Weaver,Jalal A. Hamaamen,Keeli B. Lewis,Jing Yang,Qi Liu,Izumi Kaji,Anna L. Means,R. Daniel Beauchamp
出处
期刊:American Journal of Physiology-gastrointestinal and Liver Physiology
[American Physiological Society]
日期:2021-03-24
卷期号:320 (6): G936-G957
被引量:30
标识
DOI:10.1152/ajpgi.00053.2021
摘要
We demonstrate that canonical TGFβ family signaling modulates the expression of critical tight junction proteins in colon epithelial cells, and that expression of these tight junction proteins is associated with maintenance of colon epithelial barrier function in mice.
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