Reference data and calculators for second-generation HR-pQCT measures of the radius and tibia at anatomically standardized regions in White adults

定量计算机断层扫描 医学 百分位 胫骨 人口 核医学 骨密度 内科学 统计 骨质疏松症 数学 解剖 环境卫生
作者
Stuart J. Warden,Z. Liu,Robyn K. Fuchs,Bert van Rietbergen,Sharon M. Moe
出处
期刊:Osteoporosis International [Springer Nature]
卷期号:33 (4): 791-806 被引量:18
标识
DOI:10.1007/s00198-021-06164-2
摘要

High-resolution peripheral quantitative computed tomography (HR-pQCT) is a powerful tool to assess bone health. To determine how an individual's or population of interest's HR-pQCT outcomes compare to expected, reference data are required. This study provides reference data for HR-pQCT measures acquired in a population of White adults.To provide age- and sex-specific reference data for high-resolution peripheral quantitative computed tomography (HR-pQCT) measures of the distal and diaphyseal radius and tibia acquired using a second-generation scanner and percent-of-length offsets proximal from the end of the bone.Data were acquired in White adults (aged 18-80 years) living in the Midwest region of the USA. HR-pQCT scans were performed at the 4% distal radius, 30% diaphyseal radius, 7.3% distal tibia, and 30% diaphyseal tibia. Centile curves were fit to the data using the LMS approach.Scans of 867 females and 317 males were included. The fitted centile curves reveal HR-pQCT differences between ages, sexes, and sites. They also indicate differences when compared to data obtained by others using fixed length offsets. Excel-based calculators based on the current data were developed and are provided to enable computation of subject-specific percentiles, z-scores, and t-scores and to plot an individual's outcomes on the fitted curves. In addition, regression equations are provided to convert estimated failure load acquired with the conventional criteria utilized with first-generation scanners and those specifically developed for second-generation scanners.The current study provides unique data and resources. The combination of the reference data and calculators provide clinicians and investigators an ability to assess HR-pQCT outcomes in an individual or population of interest, when using the described scanning and analysis procedure. Ultimately, the expectation is these data will be expanded over time so the wealth of information HR-pQCT provides becomes increasingly interpretable and utilized.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
吴子行完成签到,获得积分10
1秒前
下一手发布了新的文献求助10
2秒前
annie2D完成签到,获得积分10
3秒前
4秒前
橙子完成签到,获得积分10
4秒前
阿哈发布了新的文献求助10
5秒前
6秒前
噜噜晓发布了新的文献求助10
7秒前
8秒前
8秒前
Jindyla发布了新的文献求助10
9秒前
我是老大应助忞航采纳,获得10
10秒前
充电宝应助甜丝丝采纳,获得10
13秒前
13秒前
可爱的函函应助声殳香采纳,获得10
15秒前
Jindyla完成签到,获得积分10
15秒前
在水一方应助小樱桃采纳,获得10
15秒前
15秒前
陶醉的远山完成签到,获得积分10
16秒前
16秒前
呆萌鱼发布了新的文献求助10
16秒前
噜噜晓完成签到,获得积分10
18秒前
19秒前
FartKing发布了新的文献求助30
20秒前
云瑾应助清风采纳,获得10
20秒前
YYJ发布了新的文献求助10
21秒前
调研昵称发布了新的文献求助30
21秒前
善学以致用应助呆萌鱼采纳,获得10
22秒前
22秒前
23秒前
疯狂的渊思完成签到,获得积分10
23秒前
23秒前
24秒前
S-Lab Sonic完成签到,获得积分10
24秒前
忞航发布了新的文献求助10
24秒前
今后应助FartKing采纳,获得10
25秒前
27秒前
英俊的铭应助简单点采纳,获得10
28秒前
S-Lab Sonic发布了新的文献求助10
28秒前
高分求助中
Evolution 10000
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 600
Distribution Dependent Stochastic Differential Equations 500
A new species of Coccus (Homoptera: Coccoidea) from Malawi 500
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3157301
求助须知:如何正确求助?哪些是违规求助? 2808735
关于积分的说明 7878261
捐赠科研通 2467077
什么是DOI,文献DOI怎么找? 1313197
科研通“疑难数据库(出版商)”最低求助积分说明 630369
版权声明 601919