区域选择性
菲咯啉
催化作用
酰胺
组合化学
化学
重氮甲烷
多相催化
高分子化学
有机化学
作者
Yongquan Tang,Zhifeng Dai,Yan Wang,Fang Chen,Xiangju Meng,Feng‐Shou Xiao
标识
DOI:10.1002/asia.202100695
摘要
Abstract Direct C−H bond activation of heterocycles as a step‐economical and environmentally friendly approach to build the heterobiaryls motifs is highly attractive, but it still has a challenge to design and prepare a cheap and regioselective heterogeneous catalyst. To tackle this challenge, we have introduced Ni species into a porous phenanthroline‐based organic polymer donated as POP‐Phen@Ni. This heterogeneous catalyst shows excellent catalytic performances in regioselective C−H activation of heterocycles, even better than those of the corresponding homogenous catalyst. H/D exchange experiments show that the lithium bis(trimethylsilyl)amide (LiHMDS), a base added in the reaction, play a very important role during the reaction processes. We believe that this heterogeneous catalyst would open a new door for design of heterogeneous catalysts to efficiently catalyze the regioselective C−H activation of heterocycles.
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