Within the frame of SIPARIO, a project recently funded by the Italian region Emilia Romagna, it aims to virtually reconstruct both 3D audio and 360 circ video of real performances by recording and undertaking acoustic measurements inside the most historical theatres and concert halls spread all over the Europe. However, the measurement of multi-channels IRs is influenced by several other factors, including thermo-hygrometric conditions. This paper deals with the experimental analysis concerning the influence of temperature, relative humidity, and air velocity on acoustic parameters. Thermo-hygrometric variables have been varied and the variation of several room acoustic parameters has been analized. The data have been collected in order to obtained a relation between the variation of the acoustic parameters with the variation of the thermo-hygrometric variables. In further steps, a statistical analysis will be conducted to determine possible correlations between room acoustic parameters and thermo-hygrometric parameters.