亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

The effects of paravertebral blockade usage on pulmonary complications, atrial fibrillation and length of hospital stay following thoracoscopic lung cancer surgery

医学 不利影响 麻醉 心房颤动 肺癌 倾向得分匹配 心胸外科 优势比 回顾性队列研究 外科 内科学
作者
Chaoyang Tong,Jijian Zheng,Jingxiang Wu
出处
期刊:Journal of Clinical Anesthesia [Elsevier BV]
卷期号:79: 110770-110770 被引量:8
标识
DOI:10.1016/j.jclinane.2022.110770
摘要

Although combined thoracic paravertebral blockade (TPVB)-general anesthesia (GA) could improve pain control compared to GA alone after thoracoscopic lung cancer surgery, it has not been established whether this improvement in pain control could reduce associated adverse outcomes. Thus, this study aimed to explore the association between TPVB usage and adverse outcomes after thoracoscopic lung cancer surgery. Retrospective cohort study from a prospective database. A high-volume thoracic center in China. 13966 consecutive patients who received thoracoscopic lung cancer surgery from January 2016 to December 2018 in Shanghai Chest Hospital were enrolled. With a 1:1 propensity score matching (PSM) analysis, adverse outcomes between GA alone and GA-TPVB were investigated. Multivariate and multiple linear regression analysis were used to identify factors and calculate odds radio (OR) for adverse outcomes. The rate of TPVB usage was 14.8% (2070 out of 13,966). TPVB combined with GA was associated with lower rates of postoperative pulmonary complications (PPCs) (30.4% vs 33.5%, P = 0.005) and postoperative atrial fibrillation (POAF) (2.1% vs 2.9%, P = 0.041), and shorter length of hospital stay (LOS) (Median [IQR]; 5[4-5] vs 5[4-6]) days, P < 0.001) compared to GA alone. After a 1:1 PSM analysis, we investigated adverse outcomes in 2640 (1320 pairs) patients with or without TPVB usage, and this association remained existed, namely, the rates of PPCs (29.8% vs 34.2%, P = 0.014) and POAF (2.2% vs 3.6%, P = 0.028) were lower and LOS was shorter (5[4-5] vs 5[4-6] days, P < 0.001) in the GA-TPVB group. In multivariate analysis, the combination of GA plus TPVB was independent predictor for PPCs (OR = 0.879, 95%CI, 0.793–0.974, P = 0.014) and POAF (OR = 0.714, 95%CI, 0.516–0.988, P = 0.042), respectively. However, in multiple linear analysis, lower rates of PPCs and POAF associated with TPVB usage, rather than TPVB usage, were responsible for the reduced LOS. The usage of TPVB may be a feasible and adjustable approach to reduce the rates of PPCs and POAF and associated LOS in thoracoscopic lung cancer surgery.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李李发布了新的文献求助10
2秒前
李李完成签到,获得积分20
11秒前
刘宇童完成签到,获得积分10
16秒前
28秒前
Jasper应助李李采纳,获得10
42秒前
chenting完成签到 ,获得积分10
1分钟前
小付完成签到,获得积分10
1分钟前
NexusExplorer应助科研通管家采纳,获得10
1分钟前
烟消云散完成签到,获得积分10
1分钟前
汉堡包应助梦梦采纳,获得10
1分钟前
1分钟前
Orange应助reerwt采纳,获得10
2分钟前
annis完成签到,获得积分10
2分钟前
2分钟前
含蓄绿竹完成签到 ,获得积分10
2分钟前
2分钟前
reerwt发布了新的文献求助10
2分钟前
Liufgui应助sss采纳,获得10
3分钟前
梦梦完成签到,获得积分10
3分钟前
3分钟前
reerwt完成签到,获得积分20
3分钟前
3分钟前
陈元元K完成签到,获得积分10
3分钟前
英俊的铭应助科研通管家采纳,获得10
3分钟前
小二郎应助科研通管家采纳,获得10
3分钟前
3分钟前
梦梦发布了新的文献求助10
3分钟前
3分钟前
caca完成签到,获得积分0
3分钟前
科研通AI2S应助YYYCCCCC采纳,获得10
4分钟前
海鸥别叫了完成签到 ,获得积分10
5分钟前
云霞完成签到 ,获得积分10
5分钟前
朴素的山蝶完成签到 ,获得积分10
5分钟前
5分钟前
FashionBoy应助科研通管家采纳,获得10
5分钟前
Bugs完成签到,获得积分10
5分钟前
5分钟前
小八统治世界完成签到 ,获得积分10
5分钟前
tang完成签到,获得积分10
6分钟前
汉堡包应助舒服的觅夏采纳,获得10
6分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990045
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256354
捐赠科研通 3270943
什么是DOI,文献DOI怎么找? 1805146
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228