催化作用
烯丙基重排
烯烃
锰
锌
戒指(化学)
化学
镍
组合化学
金属有机化学
药物化学
立体化学
有机化学
作者
Abdoul G. Diallo,Déborah Paris,Djiby Faye,Sylvain Gaillard,Mark Lautens,Jean‐Luc Renaud
标识
DOI:10.1021/acscatal.2c00512
摘要
A general approach for the allylation of oxa- and azabenzonorbornadienes is reported by merging organophotoredox and nickel catalysis. This methodology allowed the diastereoselective allylation of various heterocyclic alkene derivatives with a broader range of allylic acetate compounds compared to previously published procedures. Moreover, no air-sensitive organometallic species and no metal reductants (such as zinc or manganese) are required for the ring opening. Mechanistic studies suggest that the ring opening proceeds through a carbometalation process.
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