A Multifunctional Luminescence Metal-Organic Framework Sensor for the Neuropathy Biomarker Glutamic Acid

Herein, a well-designed nanohybrid Fe-MIL-88NH2 with regular octahedral structure was facilely fabricated by one-step hydrothermal strategy, which as a probe presents good fluorescent stability and sensitive discrimination for Glu in aqueous solution with a detection limit of 2.04 µM. Inspired by the predominant fluorescence property of Fe-MIL-88NH2, the biological application of the probe was conducted to evaluate the degrees of Glu in Hela cells with pleasing results. Furthermore, the visualized and user-friendly handy test strips for monitoring the levels of Glu in waste water have been designed, which exhibited a satisfactory visual phenomenon and could be visualized by naked eye. Herein, a well-designed Fe-MIL-88-NH2 were facilely fabricated, which presents superior sensitive detection capacity for Glu with a detection limit of 2.04 µM. The biological application of probe was conducted to evaluating the degrees of Glu in cells. Furthermore, the corresponding portable test strips for monitoring the levels of Glu in waste water has been designed, which exhibited visually phenomenon.