化学
前药
二甲双胍
药理学
组合化学
胰岛素
内科学
生物化学
医学
作者
Kristiina M. Huttunen,Kaija Puura,Eeva Kemppainen,Piia Palonen,Jarkko Rautio,Tomi Järvinen,Jouko Vepsäläinen
出处
期刊：Synthesis
[Georg Thieme Verlag KG]
日期：2008-11-01
卷期号：2008 (22): 3619-3624
被引量：12
标识
DOI：10.1055/s-0028-1083603
摘要
The first examples of possible metformin prodrugs have been synthesized and characterized by spectroscopic methods. These five different types of chemically stable prodrugs were prepared from metformin and the corresponding halogenated promoieties. The products from unstable derivatives were also identified and reasons for the rearrangements are discussed.
科研通智能强力驱动
Strongly Powered by AbleSci AI
爱静静
zzzyyy
乐乐乐乐乐乐
kento
竹筏过海
徐叽钰
鬼见愁
华仔
睡觉晒太阳
mmyhn
eternity136
ccm
从容芮
账户已注销
rosalieshi
共享精神
Lucas
CodeCraft
不配.
Yziii
皖公网安备34019202002308
