Short interpregnancy interval and misoprostol as additive risks for uterine rupture: a case report.

BACKGROUND: Short interpregnancy interval and uterine instrumentation are risk factors for uterine rupture in subsequent pregnancies. Misoprostol as a uterotonic agent is an additive risk factor for rupture of a scarred uterus. CASE: Misoprostol induction for a term stillbirth was complicated by uterine rupture. Risk factors for this uterine rupture might have included interpregnancy intervals of < 7 months, prior uterine instrumentation, and misoprostol as a uterotonic agent. CONCLUSION: Caution and a high index of suspicion are warranted when using misoprostol as a uterotonic agent after a short interpregnancy interval.