医学
内科学
围手术期
肿瘤科
优势比
随机对照试验
化疗
荟萃分析
置信区间
腺癌
癌症
外科
作者
Danxue Huang,Feilong Sun,Liyuan Ke,Su Li
标识
DOI:10.1016/j.intimp.2024.112576
摘要
Immunotherapy in combination with chemotherapy has been approved as an initial treatment strategy for unresectable advanced gastric cancer (GC). However, the efficacy of adding immunotherapy to perioperative chemotherapy in locally advanced resectable gastric or gastroesophageal junction adenocarcinoma (GC/GEJC) remains uncertain. Therefore, a meta-analysis of randomized controlled trials (RCTs) was performed to compare the effectiveness of perioperative immune checkpoint inhibitors (ICIs) plus chemotherapy versus chemotherapy alone in patients with locally advanced resectable GC/GEJC.
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