废止
化学
催化作用
磺酰
分子间力
药物化学
双重角色
劈理(地质)
立体化学
组合化学
分子
有机化学
断裂(地质)
工程类
岩土工程
烷基
作者
Xiaoqiang Lei,Juan Feng,Qing‐Lan Guo,Yuanhe Li,Jian‐Gong Shi
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-09-28
卷期号:25 (40): 7338-7343
被引量:9
标识
DOI:10.1021/acs.orglett.3c02771
摘要
An unprecedented [2 + 3] annulation of N-sulfonyl-1,2,3-triazoles with enaminones is reported for the access of polysubstituted furans. The key to the success of the transformations lies in the use of Rh(II)-Brønsted acid as cooperative catalysts. Unlike the conventional annulations of N-sulfony-l-1,2,3-triazoles, the Rh(II)-azavinyl carbenes species play dual functions in this work, enabled by the cleavage of the C(sp2)-N bond. The mechanism studies suggested that an intermolecular rearrangement of the TsNH- group is crucial to the annulation process.
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