确定性
医学
分级(工程)
指南
证据质量
置信区间
循证医学
随机对照试验
医学物理学
精算学
替代医学
内科学
病理
认识论
哲学
土木工程
工程类
业务
作者
Daniel A. González‐Padilla,Philipp Dahm
标识
DOI:10.1016/j.euf.2023.10.014
摘要
Certainty of evidence (formerly known as quality of evidence) is defined as the extent to which our confidence in an estimate of the effect is correct or our certainty that such estimate supports a particular recommendation for a clinical practice guideline. Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) is a structured and reproducible framework for assigning a level of certainty on a per-outcome basis for evidence derived from randomized and nonrandomized studies. The level of certainty starts as high or low and can be increased or decreased after considering several criteria (eg, risk of bias, inconsistency of results, publication bias, dose-response gradient, large magnitude of effect, among others). Here we describe in brief the GRADE process for summarizing and assigning a certainty rating for evidence. PATIENT SUMMARY: The GRADE framework is a way to work out how much we can trust results from medical research studies. This helps doctors in making informed decisions with their patients.
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