[Association between circadian rhythm disorder and comorbidity of anxiety and depression in adolescents].

Adolescents are in a transition period from children to adults, during which they are prone to a variety of emotional disorders, with anxiety and depression being the most common disorders. Anxiety and depressive symptoms are highly correlated and the comorbidity of anxiety and depression is common. At the same time, the most prominent behavioral changes in adolescence are the emergence of getting up late and sleeping late, and the circadian rhythm begins to delay. Previous studies have shown that circadian rhythm is closely related to anxiety and depression, but the association between circadian rhythm disorder and comorbidity of anxiety and depression remains unclear. This article reviews the prevalence, association and potential biological mechanism of circadian rhythm disorder and comorbidity of anxiety and depression in adolescents, so as to provide a possible reference for the prevention and control of comorbidity of anxiety and depression in adolescents.青少年正处于由儿童向成人角色转变的过渡时期，该时期容易出现多种情绪障碍，其中焦虑和抑郁最为常见，且焦虑和抑郁症状具有高度相关性，通常呈现共病现象。同时，青少年时期较为突出的行为改变是晚起和晚睡，昼夜节律开始出现延迟。既往研究显示，昼夜节律与焦虑、抑郁关系密切，但昼夜节律紊乱与焦虑抑郁共病的关联尚不清楚。本文就昼夜节律紊乱与青少年焦虑抑郁共病的流行现状、关联及潜在生物学机制进行综述，为青少年焦虑抑郁共病的预防与控制提供可能的参考依据。.