Chirag Krishna,Anniina Tervi,Miriam Saffern,E. A. Wilson,Seong‐Keun Yoo,Nina Mars,Vladimir Roudko,Byuri Angela Cho,Samuel E. Jones,Natalie Vaninov,Myvizhi Esai Selvan,Zeynep H. Gümüş,Tobias L. Lenz,Miriam Mérad,Paolo Boffetta,Francisco Martínez-Jiménez,Hanna M. Ollila,Robert M. Samstein,Diego Chowell
出处
期刊:Science [American Association for the Advancement of Science (AAAS)] 日期:2024-02-22卷期号:383 (6685)被引量:8
Cancer risk is influenced by inherited mutations, DNA replication errors, and environmental factors. However, the influence of genetic variation in immunosurveillance on cancer risk is not well understood. Leveraging population-level data from the UK Biobank and FinnGen, we show that heterozygosity at the