A flexibility self-powered Band-Aid for diabetes wound healing and skin bioelectronics

Patients with diabetes who have difficulty healing wounds due to high blood sugar, persistent inflammation, oxidative stress, bacterial infections, vascular damage, and diabetic peripheral neuropathy and long-term medication can also place a heavy burden on the patient's body and economy. Traditional dressings and skin bioelectronics have single function, mechanical mismatch, high price and challenging usage, which seriously limit their wide clinical application. Here, we have developed a wearable, low-cost and self-powered Band-Aid with PVA/Ecoflex/MXene/borate/gly(glycerol) hydrogel and Ecoflex. It has excellent electrical output performance, soft texture and stable properties, and can maintain excellent performance under extreme conditions. We apply it to the repair of diabetic wounds and monitor human activity as a motion sensor. In vitro and in vivo data show that self-powered Band-Aid can accurately monitor human movement and accelerate diabetic wound repair by promoting cell proliferation and migration, collagen deposition and angiogenesis. The self-powered Band-Aid that we created demonstrates its tremendous potential not only as a motion sensor, but also as a novel technique of promoting refractory wound healing in medicine.