咔咯
化学
抗菌剂
光化学
荧光
单线态氧
光动力疗法
吸收(声学)
含时密度泛函理论
羧酸
活性氧
氧气
有机化学
分子
材料科学
生物化学
物理
量子力学
复合材料
作者
Morgana Maciél Oliveira,Gabrielle Aguiar Dantas,Luiz Antônio S. Costa,Roberto Christ Vianna Santos,Bernardo A. Iglesias
出处
期刊:Research Square - Research Square
日期:2024-01-02
标识
DOI:10.21203/rs.3.rs-3797476/v1
摘要
Abstract The mono-substituted corrole derivatives COOH-Cor and COOMe-Cor were obtained by Gryko methodology and characterized by microanalysis. In addition, we investigated experimental photophysical properties (absorption, emission by steady-state and time-resolved fluorescence) in some solvents and TDDFT calculations. Photobiological parameters such as aggregation, photostability and reactive oxygen species generation (ROS) was conducted. In addition, we also evaluated the preliminary antimicrobial photodynamic assays (aPDT) between studied corroles and bacteria strains, by white-light conditions.
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