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Recent progress in polysaccharide and polypeptide based modern moisture-retentive wound dressings

伤口愈合 伤口敷料 多糖 自愈水凝胶 医学 生物医学工程 化学 外科 材料科学 复合材料 高分子化学 生物化学
作者
Nikhil Menon,M. Kamaraj,M. Sharmila,Muthusamy Govarthanan
出处
期刊:International Journal of Biological Macromolecules [Elsevier]
卷期号:256: 128499-128499 被引量:10
标识
DOI:10.1016/j.ijbiomac.2023.128499
摘要

Wounds were considered as defects in the tissues of the human skin and wound healing is said to be a tedious process as there are possibilities of infection or inflammation due to microorganisms. Modern moisture-retentive wound dressing (MMRWD) is opening a new window toward wound therapy. It comprises different types of wound dressing that has classified based on their functionality. Selective polysaccharide-polypeptide fiber composite materials such as hydrogels, hydrocolloids, hydro fibers, transparent-film dressing, and alginate dressing are discussed in this review as a type of MMRWD. The highlight of this polysaccharide and polypeptide based MMRWD is that it supports and enhances the healing of different types of wounds by moisture absorption thus preventing infection. This study has given enlightenment on the application of selected polysaccharide and polypeptide based MMRWD that enhances wound healing actions still it has been observed that the composite wound healing dressing is more effective than the single one. The nano-sized materials (synthetic nano drugs and phyto drugs) were found to increase the efficiency of healing action while coated in the wound dressing material. Future research is required to find out more possibilities of the different composite types of wound dressing in the healing action.
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