粒体自噬
脂质过氧化
品脱1
细胞生物学
程序性细胞死亡
GPX4
化学
顺铂
线粒体
自噬
活性氧
氧化应激
癌症研究
生物
细胞凋亡
生物化学
过氧化氢酶
谷胱甘肽过氧化物酶
化疗
遗传学
作者
Qisheng Lin,Shu Li,Haijiao Jin,Hong Cai,Xuying Zhu,Yuanting Yang,Jingkui Wu,Chaojun Qi,Xinghua Shao,Jialin Li,Kaiqi Zhang,Wenyan Zhou,Minfang Zhang,Jiayi Cheng,Leyi Gu,Shan Mou,Zhaohui Ni
摘要
knockout cisplatin-treated mice. Ferrstatin-1, a synthetic antioxidative ferroptosis inhibitor, rescued iron accumulation, lipid peroxidation and ferroptosis caused by inhibition of mitophagy. Thus, the present study elucidated a novel mechanism by which both BNIP3-mediated and PINK1-PARK2-mediated mitophagy protects against cisplatin-induced renal tubular epithelial cell ferroptosis through the ROS/HO1/GPX4 axis.
科研通智能强力驱动
Strongly Powered by AbleSci AI
PDF的下载单位、IP信息已删除
(2025-6-4)
无极微光
伶俐妙海
cdercder
Copyright
phdbio
yjh123
Nexus
Nole
huang
潇洒的惋清
arniu2008
sagitar
行走的荷尔蒙
tiptip
kimyb
Criminology34
Kao
OK
雪满头
pluto
皖公网安备34019202002308
