Perioperative anaphylaxis associated with peripheral inserted central catheter: A retrospective observational study

Background: Peripheral Inserted Central Catheter (PICC) is a commonly utilized medical device for long-term intravenous therapy in healthcare settings. However, there has been a notable increase in anaphylaxis associated with PICC catheterization, which should not be neglected. Aims: The purpose is to raise awareness about the occurrence of anaphylaxis or anaphylactoid reactions associated with PICC and to emphasize the need to explore effective methods to prevent this emergency event in the future. Method: This retrospective observational study was conducted at Sun Yat-sen University Cancer Center between January 2021 and August 2023. Results: 0.10% (13 out of 12,612) of cancer patients suffered from anaphylactic reactions during PICC catheterization. The duration time of anaphylaxis or anaphylactoid reactions was approximately 8 min, with a range of 5–10 min. The signs and symptoms combined with respiratory and cardiovascular system symptoms. Most patients were relieved spontaneously by oxygen inhalation and completed catheterization after their symptoms were alleviated. Conclusion: The increasing incidence of anaphylaxis related to PICC catheterization necessitates greater awareness among healthcare providers. Further research is needed to identify the exact culprits during PICC insertion and develop effective strategies for preventing anaphylactic reactions.