Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas

(Cell Stem Cell 28, 2000–2008.e1–e4; November 4, 2021) In the originally published version of our manuscript, in Figure 3, we made an error when labeling the axes in Figures 3C and 3G. In Figure 3C, four sections were analyzed per mouse, and the numbers given are the average numbers of positive cells per section, with each data point representing one animal and not positive cells per mouse. In Figure 3G (third column), only Ngn3-CreERT; AKITA mice are analyzed, without any lineage tracing, with cells expressing INS or SST quantified. To address this, we have now updated the graph labels, and an updated Figure 3 is included below. We apologize for the oversight and for any confusion caused. Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreasGribben et al.Cell Stem CellSeptember 2, 2021In BriefA better understanding of adult beta cell neogenesis would open new approaches for diabetes treatment. Gribben et al. used lineage tracing and scRNA-seq to characterize a duct-resident somatostatin-positive endocrine progenitor cell population that is a source of beta cells in homeostasis and during diabetes. Full-Text PDF Open Access