间变性大细胞淋巴瘤
医学
节的
免疫分型
淋巴瘤
病理
外周T细胞淋巴瘤
未另行规定
滤泡性淋巴瘤
T细胞
爱泼斯坦-巴尔病毒
病毒
免疫学
内科学
流式细胞术
免疫系统
作者
Naoki Oishi,Andrew L. Feldman
标识
DOI:10.1016/j.path.2023.01.011
摘要
This review summarizes the current understanding of mature T-cell neoplasms predominantly involving lymph nodes, including ALK-positive and ALK-negative anaplastic large cell lymphomas, nodal T-follicular helper cell lymphoma, Epstein-Barr virus-positive nodal T/NK-cell lymphoma, and peripheral T-cell lymphoma (PTCL), not otherwise specified. These PTCLs are clinically, pathologically, and genetically heterogeneous, and the diagnosis is made by a combination of clinical information, morphology, immunophenotype, viral positivity, and genetic abnormalities. This review summarizes the pathologic features of common nodal PTCLs, highlighting updates in the fifth edition of the World Health Organization classification and the 2022 International Consensus Classification.
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